Endocrine Abstracts

Subclinical hyperthyroidism is a biochemical diagnosis defined with suppressed levels of TSH and normal levels of thyroid hormones. One of the main metabolic responses to thyroid hyperfunction is peripheral lipolysis and release of free fatty acids (FFA). The aim of this study was to compare levels of cholesterol, LDL, HDL and triglycerides in persons with subclinical hyperthyroidism to age and BMI matched euthyroid healthy control. We evaluated 45 persons in two groups: 1st g...

Subclinical hypothyroidism is a biochemical diagnosis defined with elevated levels of TSH and normal levels of thyroid hormones. The most common abnormality linked to this condition is hypercholesterolemia. The aim of this study was to search for MSy among the persons with subclinical hypothyroidism which was already proven to have hypercholesterolemia when compared to healthy control. MSy was identified in those with elevated triglycerides (Tgc), reduced HDL and elevated fast...

Several studies show that characteristics of metabolic syndrome are often seen in patients with adrenal incidentaloma. The aim of our study was to evaluate metabolic factors in these patients. 208 patients (148 female and 60 male, age 55.08±11.02 y’s and BMI 27.91±4.6 kg/m2) were admitted and biochemical, endocrine testing were performed. Lipid status: cholesterol 5.77±1.26 mmol/L, triglyceride 1.92±0.98 mmol/L. 113(55%) patients were hypert...

POF is a disease of unclear origin affecting women under age 40. They are at high risk of cardiovascular diseases (CVD).The objective of this study was to compare the lipid status and atherogenic indexes - total cholesterol/high density lipoprotein (TC/HDL) and low density lipoprotein/HDL (LDL/HDL) - of women with POF with healthy women of the same age and the same BMI.We evaluated 54 women in two groups. 1st group: 31 women with P...

Introduction: Secretory adrenal tumors sensitive to luteinizing hormone (LH) and/or human chorionic gonadotropin (hCG) are well documented in the literature. LH and hCG share a mutual LH/hCG receptor and a comparable physiological role.Objective: The aim of our study was to evaluate the response of adrenal steroids (cortisol, aldosterone and dehydroepiandrosterone sulphate (DHEAS)) to exogenous hCG stimulation in menopausal patients with adrenal incident...

Premature ovarian insufficiency (POI) is characterized by cessation of ovarian function before the age of 40. Variable clinical presentation often postpones the diagnosis. The aim of our study was to assess whether there is a typical menstrual cycles pattern in patients with POI. We have evaluated 101 women, age 36.7±5.78 y. FSH=78.81±37.43 IU/l, E2<50 pg/dl, with confirmed POI referred to our Clinic between 2014 and 2018. Menstrual cycles characteristics were de...

Introduction: It is presumed that hiccups are a vestigial reflex in mammals. They are rather common in healthy subjects. Persistent hiccups (lasting >48 h) are a serious clinical sign, and documented in a number of debilitating conditions. According to the available literature persistent hiccups in Addisonian crisis have been previously documented in only two patients.Case report: In July 2018, a 39 year old man checked into the ER complaining of nau...

It has been more than 70 years since the first adrenal incidentalomas (AI) were described. Most of these tumors are non-secreting, and are found in 4–7% of adult population. Patients with subclinical hypercortisolism (or autonomous cortisol secretion) (SH) are observed in 1–29% of patients with AIs. Evidence suggests that this condition may be associated with higher prevalence of diabetes, obesity, hypertension and osteoporosis.Between 1999 and...

It has been more than 70 years since the first adrenal incidentalomas (AI) were described. Most of these tumors are non-secreting, and are found in 4–7% of adult population. Patients with subclinical hypercortisolism (or autonomous cortisol secretion) (SH) are observed in 1–29% of patients with AIs. Evidence suggests that this condition may be associated with higher prevalence of diabetes, obesity, hypertension and osteoporosis.Between 1999 and...

Adrenal hemangioma is a rare adrenal tumour usually presented as incidental finding in asymptomatic patients. Due to its radiographic features sometimes it’s difficult to differentiate them from other malignant lesions. We present a 55-years-old men admitted to our department with adrenal incidentaloma size 5×4 cm confirmed by MSCT scan. Active phaeochromocythoma was excluded by normal urinary catecholamines. Endocrine evaluations revealed normal midnight cortisol, w...